Which histological feature is indicative of epitheliotrophic T-cell lymphoma?

The histological feature indicative of epitheliotrophic T-cell lymphoma is the presence of Pautrier's aggregates in the epidermis. These aggregates consist of clusters of neoplastic T-cells that infiltrate the epidermis, leading to characteristic findings associated with this type of lymphoma. The formation of Pautrier's microabscesses is a hallmark of mycosis fungoides, which is a form of epitheliotrophic T-cell lymphoma, illustrating how malignant T-cells can invade and proliferate within the epidermal layer of the skin.

Understanding this histological feature is crucial for identifying the disease and differentiating it from other cutaneous lymphomas or skin conditions. The presence of these aggregates is observed during microscopic examination of skin biopsies, providing a clear link between the histopathological findings and the diagnosis of this specific lymphoma type.