Which chemotherapy protocol is commonly used for treating lymphoma in dogs?

The CHOP protocol is a well-established chemotherapy regimen used specifically for treating lymphoma in dogs. This protocol includes a combination of four drugs: cyclophosphamide, doxorubicin, vincristine, and prednisone. The combination targets various aspects of cancer cell growth and proliferation, making it effective in achieving remission in canine lymphoma cases.

This protocol is favored because it has shown success in managing intermediate to high-grade lymphomas, which are common in dogs. It is also designed to provide a balanced approach that minimizes the risk of developing resistance while maximizing the therapeutic effects against the cancer. The choice of each drug in the regimen is based on their individual effects on lymphoma cells, as well as their tolerability in dogs.

While other protocols, such as R-CHOP, include rituximab and have specific applications in veterinary oncology, the CHOP protocol remains the cornerstone treatment recognized for its efficacy and history of use in the field. The other protocols mentioned are not standard treatments for lymphoma in dogs, making CHOP the most applicable answer in this context.